humana

Friday marked the official end to Indianapolis-based Anthem’s bid to merge with Cigna, and the second time in recent months a major health insurance merger has failed.

It underscores the uphill regulatory battle that big health insurers face in trying to join forces.

Anti-trust officials blocked mergers between Humana and Aetna, and Anthem and Cigna this year. Those four have something in common: they’re among their industry’s biggest, top-earning companies.