The Marion County Sheriff’s Office issued a warning about a new synthetic opioid called cychlorphine is being linked to a growing number of fatal overdoses across the Midwest — including in Ohio, Kentucky and Tennessee.

Thousands descended on the Indiana Statehouse Saturday to oppose the Trump presidency and call for ‘No Kings.’

Former Indiana Gov. Mitch Daniels is warning that the nation’s nearly $39 trillion debt poses serious risks to the economy and younger generations, urging lawmakers and business leaders to take action.

Republican Alexandra Wilson was approved for the May ballot after months of legal challenges and a White House pressure campaign to end her candidacy.

Despite threats that he would back primary challenges against lawmakers who came out against redistricting, Gov. Mike Braun Tuesday issued several endorsements for House Republicans who voted down the effort.

A federal judge has struck down Indiana’s ban on using student IDs to vote. The case could impact roughly 40,000 people.

The union representing professional staff at the Indiana State Teachers Association filed several unfair labor practice charges with the National Labor Relations Board.

Indiana lawmakers debated a bill that would require public colleges to accept the Classic Learning Test alongside the SAT and ACT. Supporters call it a “back to basics” option, while testing officials question its validation and security.

A bill that would transfer significant financial and operational control of Indianapolis Public Schools to a new mayoral-appointed body passed its first vote on Wednesday.

The Marion County Sheriff’s Office issued a warning about a new synthetic opioid called cychlorphine is being linked to a growing number of fatal overdoses across the Midwest — including in Ohio, Kentucky and Tennessee.

In 2022, the MACRO-B project set out to reduce opioid overdose deaths in Black Indianapolis neighborhoods. Those community members, education and harm reduction tools shaped the project's work over the next three years.  Overdose deaths among Black people in target areas decreased by 45 percent by the end of the project.  

Indiana lawmakers want to close a loophole allowing the sale of hemp products with high THC levels. Many industry workers say it could force them to close.

Federal funding that supports artists across Indiana has been terminated by the Trump Administration.

Author Craig Martin takes us on a romp through 1800's Lafayette in the book "Percy Hare and the Girl in the Game - An early legend of the Lafayette town." Nick Schenkel has the review.

Author Paco Calvo delves into the world of thinking plants in his book: “Planta Sapiens: The New Science of Plant Intelligence.” Nick Schenkel has the review.

Lawmakers have been in a stalemate for over 60 days about funding the entire department, which includes agencies that oversee immigration enforcement, disaster relief, cybersecurity and the U.S. Coast Guard.

Six months into a ceasefire that promised an end to the war and a surge of aid for Gaza, people say recovery hasn't even yet begun.

The U.N. looks for a quick solution to get cargo ships with fertilizer through the Strait of Hormuz, to prevent a global food crisis.